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Search Results to Roberta Pelanda

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Pelanda, Roberta

One or more keywords matched the following items that are connected to Pelanda, Roberta

Item Type	Name
Academic Article	Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification.
Academic Article	From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins.
Academic Article	A prematurely expressed Ig(kappa) transgene, but not V(kappa)J(kappa) gene segment targeted into the Ig(kappa) locus, can rescue B cell development in lambda5-deficient mice.
Academic Article	Cre recombinase-controlled expression of the mb-1 allele.
Academic Article	Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo.
Academic Article	Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens.
Academic Article	Receptor editing for better or for worse.
Academic Article	Ig allotypic inclusion does not prevent B cell development or response.
Academic Article	BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling.
Academic Article	Antigen and cytokine receptor signals guide the development of the na?ve mature B cell repertoire.
Academic Article	Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes.
Academic Article	B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.
Academic Article	Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components.
Academic Article	Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation.
Academic Article	Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.
Academic Article	Efficient generation of B lymphocytes by recognition of self-antigens.
Academic Article	Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice.
Concept	Antigen Presentation
Concept	Receptors, Antigen, T-Cell
Concept	Antigen-Presenting Cells
Concept	Receptors, Antigen, B-Cell
Concept	B7-2 Antigen
Academic Article	B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia.
Academic Article	Dual immunoglobulin light chain B cells: Trojan horses of autoimmunity?
Academic Article	Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response.
Academic Article	Activation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodies.
Academic Article	CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
Academic Article	Receptor editing and genetic variability in human autoreactive B cells.
Grant	Analysis of Human B Cell Tolerance in Humanized Mice
Grant	Human B Cell Development and Function in Humanized Mice Expressing Human BAFF
Grant	Tolerance in polyclonal and oligoclonal immune systems
Grant	Tolerance in Polyclonal and Oligoclonal Immune Systems
Grant	Modulatory signaling motifs in B cell antigen receptor function
Grant	Testing an alternative model of central B cell tolerance
Academic Article	Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance.
Academic Article	Conditional Selection of B Cells in Mice With an Inducible B Cell Development.
Academic Article	Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus.
Concept	Clonal Selection, Antigen-Mediated
Academic Article	Active PI3K abrogates central tolerance in high-avidity autoreactive B cells.
Academic Article	LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling.
Grant	Role and mechanisms of the PI3K pathway in B cell tolerance
Academic Article	Histone H2A-Reactive B Cells Are Functionally Anergic in Healthy Mice With Potential to Provide Humoral Protection Against HIV-1.
Academic Article	Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice.
Academic Article	B-cell intrinsic and extrinsic signals that regulate central tolerance of mouse and human B cells.
Academic Article	CD19 Is Internalized Together with IgM in Proportion to B Cell Receptor Stimulation and Is Modulated by Phosphatidylinositol 3-Kinase in Bone Marrow Immature B Cells.

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